Retinoblastoma Program

Steps Involved in IVF:

Procedure Description

Retinoblastoma is a rare cancer of the retina that typically affects children under the age of five. This condition occurs when the cells of the retina, responsible for detecting light and sending signals to the brain, begin to grow uncontrollably. Retinoblastoma can be inherited or develop sporadically, and while rare, it represents a critical concern due to its potential impact on vision and, if untreated, the spread of cancer beyond the eye.

The Retinoblastoma Program involves a multi-disciplinary approach, combining expertise from oncology, ophthalmology, and radiology to provide comprehensive care. Treatment varies depending on the stage of cancer at the time of diagnosis. Early detection can lead to localized treatments that save both the eye and vision, while more advanced cases may require more aggressive interventions.

Primary treatment options for retinoblastoma include focal therapies such as laser photocoagulation, cryotherapy, and chemotherapy, either applied locally or systemically. Advanced cases may require more invasive approaches like enucleation (removal of the eye) or external beam radiotherapy. Specialists in the Retinoblastoma Program aim to preserve vision whenever possible while also preventing the spread of cancer to other areas of the body.

Procedure Duration

The duration of treatment for retinoblastoma depends on various factors, including the stage of cancer, the child’s overall health, and the selected treatment methods. Typically, the treatment process is divided into distinct phases, which can last several months to years depending on the complexity of the case.

Initial Evaluation and Staging:

The first phase of treatment involves a thorough evaluation, which includes diagnostic imaging, such as ultrasound, MRI, or CT scans, to determine the stage of the disease. This phase may take a few weeks to complete, as it involves consultations with specialists and development of a personalized treatment plan.

Active Treatment Phase:

The active treatment phase varies depending on the chosen therapeutic modality. Chemotherapy, for instance, can be administered over several months in cycles, typically involving one treatment every few weeks. Localized treatments such as laser therapy or cryotherapy are often performed in conjunction with chemotherapy, and these procedures are relatively quick, often completed in under an hour. More invasive treatments, such as enucleation, may require longer surgical intervention followed by recovery time in a hospital.

Follow-up and Monitoring:

After the primary treatment, follow-up visits are crucial to monitor for recurrence. Retinoblastoma can recur, and ongoing monitoring through regular eye exams and imaging tests is necessary for several years after treatment concludes. Follow-up schedules vary but can start with visits every few months, eventually tapering off to annual exams as the child ages and shows no signs of recurrence.

Benefits of the Procedure

  • Preservation of Vision: In early-stage retinoblastoma, treatment can often save vision and avoid the need for invasive surgery.
  • High Cure Rates: When diagnosed early, retinoblastoma has an excellent prognosis with cure rates as high as 95% in localized cases.
  • Tailored Treatment Plans: Multidisciplinary teams create individualized plans based on the stage of cancer and the child's unique needs.
  • Advanced Technologies: Use of cutting-edge technology such as intra-arterial chemotherapy and focal therapies minimizes damage to surrounding tissue.
  • Preventing Metastasis: Early intervention helps to prevent the spread of cancer to other areas of the body, particularly the brain and spine.

Potential Destinations

1. United States:


Known for its cutting-edge cancer treatment centers, the United States offers advanced options for retinoblastoma treatment. Medical tourists are attracted by the availability of clinical trials and the expertise of specialists in pediatric oncology and ophthalmology.

2. United Kingdom:


The UK is home to several renowned children's hospitals with comprehensive retinoblastoma programs. Families often choose this destination for its high standards of care and access to experienced oncologists who specialize in rare pediatric cancers.

3. Germany:


Germany has a well-developed healthcare system that integrates advanced cancer treatment technologies. Medical tourists are drawn to Germany for its state-of-the-art treatment options, including proton therapy and localized chemotherapy for retinoblastoma.

4. India:


India offers high-quality care at a lower cost, making it a popular destination for retinoblastoma treatment. With well-established pediatric oncology centers and access to advanced therapies, India provides effective treatment options for international patients.

5. Spain:


Spain has a growing reputation for excellence in cancer treatment. Pediatric oncology programs in Spain offer personalized treatment for retinoblastoma with a focus on innovative and less invasive approaches.

Risks & Considerations

  • Vision Loss: In advanced cases, retinoblastoma may lead to partial or complete loss of vision, especially if enucleation is necessary.
  • Recurrence: Despite successful treatment, retinoblastoma can recur, requiring additional therapies and lifelong monitoring.
  • Side Effects of Chemotherapy: Chemotherapy, while effective in treating retinoblastoma, can lead to side effects such as nausea, immune suppression, and hair loss.
  • Radiation Risks: External beam radiation therapy, used in some cases, can cause damage to surrounding healthy tissues and lead to long-term complications.
  • Psychological Impact: The treatment process, particularly if it involves loss of vision or eye removal, can have lasting psychological effects on both the child and family.

How to Choose the Right Doctor and Hospital

When selecting a doctor and hospital for retinoblastoma treatment, it is important to choose a facility with specialized expertise in pediatric oncology and ophthalmology. Look for hospitals with a dedicated retinoblastoma program, where multidisciplinary teams work together to provide holistic care.

Seek out specialists who have extensive experience treating retinoblastoma and who can offer a variety of treatment options, from localized therapies to systemic chemotherapy. Additionally, consider the hospital’s track record with pediatric patients and its access to cutting-edge technologies, such as intra-arterial chemotherapy or advanced radiation techniques. Families may also wish to seek a second opinion to ensure they are choosing the most appropriate treatment plan for their child's unique needs.

To receive a free quote for this procedure please click on the link: https://www.medicaltourism.com/get-a-quote

Patients are advised to seek hospitals that are accredited by Global Healthcare and only work with medical tourism facilitators who are certified by Global Healthcare Accreditation or who have undergone certification from the Certified Medical Travel Professionals (CMTP). This ensures that the highest standards in the industry are met. GHA accredits the top hospitals in the world. These are the best hospitals in the world for quality and providing the best patient experience. Click the link to check out hospitals accredited by the Global Healthcare Accreditation: https://www.globalhealthcareaccreditation.com

Frequently Asked Questions

What actually happens during hyperstimulation of the ovaries?

The patient will take injectable FSH (follicle stimulating hormone) for eight to eleven days, depending on how long the follicles take to mature. This hormone is produced naturally in a woman’s body causing one egg to develop per cycle. Taking the injectable FSH causes several follicles to develop at once, at approximately the same rate. The development is monitored with vaginal ultrasounds and following the patient’s levels of estradiol and progesterone. FSH brand names include Repronex, Follistim, Menopur, Gonal-F and Bravelle. The patient injects herself daily.

What happens during egg retrieval?

When the follicles have developed enough to be harvested, the patient attends an appointment  where she is anesthetized and prepared for the procedure. Next, the doctor uses an ultrasound probe to guide a needle through the vaginal wall and into the follicle of the ovary. The thin needle draws the follicle fluid, which is then examined by an embryologist to find the eggs. The whole process takes about 20 minutes.

What happens to the eggs?

In the next step, the harvested eggs are then fertilized. If the sperm from the potential father, or in some cases, anonymous donor, has normal functionality, the eggs and sperm are placed together in a dish with a nutrient fluid, then incubated overnight to fertilize normally. If the sperm functionality is suboptimal, an embryologist uses Intracytoplasmic Sperm Injection to inject a single sperm into a single egg with an extremely precise glass needle.  Once fertilization is complete, the embryos are assessed and prepared to be transferred to the patient’s uterus.

How are the embryos transferred back to the uterus?

The doctor and the patient will discuss the number of embryos to be transferred. The number of successfully fertilized eggs usually determines the number of eggs to be placed in the uterus. Embryos are transferred to the uterus with transabdominal ultrasound guidance. This process does not require anesthesia, but it can cause minor cervical or uterine discomfort. Following transfer, the patient is advised to take at least one days bed rest and two or three additional days of rest, then 10 to 12 days later, two pregnancy tests are scheduled to confirm success. Once two positive tests are completed, an obstetrical ultrasound is ordered to show the sac, fetal pole, yolk sac and fetal heart rate.

Embryoscope©

Built into this technology there is a microscope with a powerful camera that allows the uninterrupted monitoring of the embryo during its first hours of life. In this way, we can keep a close eye on the embryo, from the moment when the oocyte is inseminated and begins to divide into smaller and smaller cells, until it can be transferred to the uterus.

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