PRP Stem Cells Treatment for Infertility

Steps Involved in IVF:

Procedure Description

Platelet-rich plasma (PRP) and stem cell treatments are emerging as promising options for individuals facing infertility issues. Infertility, whether in males or females, can stem from various causes like hormonal imbalances, diminished ovarian reserves, poor sperm quality, or uterine abnormalities. The combination of PRP and stem cell therapies aims to address these issues at a cellular level, potentially enhancing reproductive potential.

The PRP and stem cell treatment process involves isolating components from a patient's blood to harness their regenerative abilities. PRP is derived from a patient’s own blood, which is processed to concentrate the platelets rich in growth factors. These growth factors play a crucial role in tissue regeneration, cellular repair, and inflammation reduction. When PRP is combined with stem cells, which have the ability to differentiate into various cell types, the treatment targets specific reproductive tissues, aiming to improve their function and structure. In females, it may be used to rejuvenate the ovaries or endometrial lining. In males, it can improve sperm quality and boost the chances of conception.

These treatments are performed in controlled clinical settings using advanced technology. The process begins with a simple blood draw from the patient, which is then processed to concentrate PRP and/or stem cells. This biologically enriched mixture is then carefully injected into targeted reproductive areas, such as the ovaries or uterine lining in females, or testicular tissue in males, to encourage cellular repair, growth, and better functionality. While the treatment itself may be relatively straightforward, the procedure’s efficacy and applicability depend on the patient’s specific condition and underlying causes of infertility.

Procedure Duration

PRP and stem cell treatments for infertility are typically performed over several sessions, as determined by a fertility specialist based on the patient's condition. The initial consultation includes an in-depth evaluation of the patient’s reproductive health, diagnosis of infertility causes, and a review of medical history. Following this assessment, the clinician will schedule the procedure based on the patient's cycle (for females) or at an optimal time for best results.

The PRP process, which begins with drawing a small amount of the patient’s blood, usually takes about 30 to 45 minutes. Once the blood is collected, it is processed through centrifugation to separate and concentrate the PRP. In cases where stem cells are also used, these are either harvested from the patient's own body fat (autologous stem cells) or are derived from other sources like bone marrow. The preparation and processing of stem cells may take additional time, usually around an hour.

The treatment itself is minimally invasive and can often be performed on an outpatient basis. The administration of PRP and/or stem cells through targeted injections is guided by ultrasound or other imaging techniques to ensure precision. Post-procedure, patients may experience mild discomfort at the injection site, but this typically subsides within a few hours to a day. Recovery is usually quick, and most patients can resume normal activities within 24 to 48 hours. However, multiple sessions might be required to see noticeable results, with intervals of weeks or months between treatments.

Benefits

  • Minimally Invasive Treatment: PRP and stem cell therapies are typically less invasive than traditional fertility treatments, with no need for major surgery or extended hospital stays.
  • Potential to Enhance Ovarian Reserve: In women with diminished ovarian reserve or poor egg quality, PRP may rejuvenate ovarian tissue, leading to improved ovarian response.
  • Improves Uterine Lining: For women struggling with a thin endometrial lining, PRP injections can stimulate growth factors to enhance the lining, improving the chances of embryo implantation.
  • Improvement in Sperm Quality: For male infertility, stem cell therapy has shown promise in boosting sperm count, quality, and motility, enhancing the overall reproductive potential.
  • Use of Autologous Material: Since PRP and stem cells are derived from the patient’s own body, the risk of rejection or allergic reaction is greatly minimized.

Potential Destinations

  • Greece: Greece has made significant advancements in regenerative medicine and fertility treatments. With experienced specialists, cutting-edge clinics, and comprehensive care protocols, the country is emerging as a preferred destination for PRP and stem cell treatments for infertility.
  • Spain: Spain is renowned for its fertility clinics and progressive reproductive technologies. High standards of medical care, paired with affordable treatment costs, make it an attractive option for those seeking PRP and stem cell therapies.
  • Turkey: Turkey offers world-class fertility centers, some with a strong focus on regenerative medicine and fertility enhancement. The country is known for providing treatments that adhere to international quality standards at comparatively lower costs.
  • Mexico: For those in North America, Mexico provides a convenient option for PRP and stem cell treatments. With several clinics specializing in reproductive health and regenerative medicine, Mexico combines expertise with affordability, drawing international patients seeking fertility care.
  • Thailand: Thailand's fertility centers have earned a global reputation for their excellence in offering advanced treatments, including PRP and stem cell therapies. The combination of state-of-the-art facilities and highly trained medical professionals makes it a top destination for medical tourism.

Risks & Considerations

  • Uncertain Success Rates: PRP and stem cell therapies are still relatively new in the context of infertility, and research on their long-term efficacy is ongoing. Success rates may vary based on the underlying cause of infertility and the patient's overall health.
  • Multiple Sessions May Be Required: One treatment session may not suffice, and some patients may require several sessions over a period of time to achieve optimal results, which could affect costs and treatment timelines.
  • Limited Regulation: In some regions, PRP and stem cell treatments might not be as regulated as traditional fertility treatments, leading to variability in the quality and safety standards of the procedures.
  • Potential for Mild Discomfort: Although minimally invasive, patients might experience some discomfort, bruising, or swelling at the injection sites, which typically resolve within a short period.
  • Variable Costs and Coverage: The cost of PRP and stem cell treatments can be significant, and insurance coverage may vary widely. It is essential to understand the financial implications before proceeding with treatment.

How to Choose the Right Doctor and Hospital

Selecting the right doctor and hospital for PRP and stem cell treatment is critical for success. Look for a fertility specialist who has experience in regenerative therapies and a solid understanding of both PRP and stem cell applications in treating infertility. Verification of the specialist’s credentials, professional memberships, and years of experience in this field is crucial.

When choosing a hospital or clinic, prioritize those that have a strong reputation for fertility treatments and use advanced technology. Seek out clinics with a transparent approach to care, patient-centered treatment plans, and a proven track record in PRP and stem cell therapies for infertility. Reading patient testimonials and reviews can also provide insight into the facility's reputation and success rates.

To receive a free quote for this procedure please click on the link: https://www.medicaltourism.com/get-a-quote

Patients are advised to seek hospitals that are accredited by Global Healthcare and only work with medical tourism facilitators who are certified by Global Healthcare Accreditation or who have undergone certification from the Certified Medical Travel Professionals (CMTP). This ensures that the highest standards in the industry are met. GHA accredits the top hospitals in the world. These are the best hospitals in the world for quality and providing the best patient experience. Click the link to check out hospitals accredited by the Global Healthcare Accreditation: https://www.globalhealthcareaccreditation.com

Frequently Asked Questions

What actually happens during hyperstimulation of the ovaries?

The patient will take injectable FSH (follicle stimulating hormone) for eight to eleven days, depending on how long the follicles take to mature. This hormone is produced naturally in a woman’s body causing one egg to develop per cycle. Taking the injectable FSH causes several follicles to develop at once, at approximately the same rate. The development is monitored with vaginal ultrasounds and following the patient’s levels of estradiol and progesterone. FSH brand names include Repronex, Follistim, Menopur, Gonal-F and Bravelle. The patient injects herself daily.

What happens during egg retrieval?

When the follicles have developed enough to be harvested, the patient attends an appointment  where she is anesthetized and prepared for the procedure. Next, the doctor uses an ultrasound probe to guide a needle through the vaginal wall and into the follicle of the ovary. The thin needle draws the follicle fluid, which is then examined by an embryologist to find the eggs. The whole process takes about 20 minutes.

What happens to the eggs?

In the next step, the harvested eggs are then fertilized. If the sperm from the potential father, or in some cases, anonymous donor, has normal functionality, the eggs and sperm are placed together in a dish with a nutrient fluid, then incubated overnight to fertilize normally. If the sperm functionality is suboptimal, an embryologist uses Intracytoplasmic Sperm Injection to inject a single sperm into a single egg with an extremely precise glass needle.  Once fertilization is complete, the embryos are assessed and prepared to be transferred to the patient’s uterus.

How are the embryos transferred back to the uterus?

The doctor and the patient will discuss the number of embryos to be transferred. The number of successfully fertilized eggs usually determines the number of eggs to be placed in the uterus. Embryos are transferred to the uterus with transabdominal ultrasound guidance. This process does not require anesthesia, but it can cause minor cervical or uterine discomfort. Following transfer, the patient is advised to take at least one days bed rest and two or three additional days of rest, then 10 to 12 days later, two pregnancy tests are scheduled to confirm success. Once two positive tests are completed, an obstetrical ultrasound is ordered to show the sac, fetal pole, yolk sac and fetal heart rate.

Embryoscope©

Built into this technology there is a microscope with a powerful camera that allows the uninterrupted monitoring of the embryo during its first hours of life. In this way, we can keep a close eye on the embryo, from the moment when the oocyte is inseminated and begins to divide into smaller and smaller cells, until it can be transferred to the uterus.

Orthopedics Stem Cell

Knee

Research on mesenchymal stem cells regenerative properties in knee osteoarthritis. In these studies, researchers suggest that Stem Cell Therapy has the potential to regenerate lost cartilage, stop and reverse cartilage degeneration, provide pain relief, and improve patient mobility.

Shoulder

Stem Cell Therapy as an Alternative to Rotator Cuff & Shoulder Replacement Surgery. Stem cell therapy may offer an excellent alternative for patients looking to avoid shoulder joint replacement surgery, as well as many other surgical treatments for shoulder pain.

Ankle

If you suffer from chronic or acute ankle pain or instability due to arthritis, cartilage loss, ligament strain or tear, or tendon damage, then you may benefit from non-surgical stem cell treatments or stem cell-enhanced surgery.

Back Pain

Patients now have a minimally invasive option. Stem cell therapy for back pain and disc herniations can potentially repair the damaged disc or facet joint, restore function, rehydrate the disc, and ultimately alleviate chronic pain.

Anti-Aging Stem Cell

Hair Loss

Stem cell therapy and PRP therapy have been shown to be most effective for: Those in the early stages of hair loss, patients who are not viable candidates for surgery and women who prefer to avoid hair surgery.

Facial Anti-Aging

Aesthetic Anti-Aging. The Aesthetic Stem Cell Localized Treatment is a non-surgical minimally invasive procedure to enhance the appearance of aging skin and hair restoration. This all-natural technique combines dermal injections of bone marrow or adipose tissue derived stem cells and growth factors.

Fertility Stem Cell

Endometrial PRP

The stem cells used for treatment of a thin endometrium include mesenchymal stem cells. In addition, successful repair of the endometrium in pregnancy with stem cells has been reported previously.

Low Ovarian Reserve (PRP)

The treatment uses PRP (Platelet-Rich-Plasma), which with stem cell therapy is the novel therapeutic approach for restoring the quality of the ovarian reserve.Your PRP will contain a physiologic balance of platelets, growth factors and white blood cells tailored specifically for you.

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