IVF with Egg / Sperm Donor
Steps Involved in IVF:
What is Egg donation?
Egg donation is a fertility treatment process where eggs from another person, usually a donor between the ages of 20 and 30, are fertilized with sperm from the intended father or a sperm donor and then transferred to the uterus of the woman who is trying to conceive. Egg donation is most common among women over the age of 40 or those with low ovarian reserves. The procedure has been in practice since the 1980s and has helped thousands of women achieve pregnancy.
Who is an eligible donor?
Egg donors are usually women between the ages of 20 and 30 who are able to pass a rigorous screening process to ensure the donation is as viable as possible for the recipient. Egg donation involves not only physical compatibility but also emotional, psychological and legal components which are included in the screening process. Standard testing includes:
- Complete medical history and pelvic screening
- Drug screening
- Infectious disease screening
- Ovarian reserve screening
- Psychological screening
How does the donation process work?
There are several steps involved in egg donation. The first step is for the recipient patient to be screened to see if she is a good candidate for the process and to check compatibility with the donor. The donor can be a friend or family member or a completely anonymous donor. Once all of the screenings are complete and a match is made, the recipient and the donor will be placed on prescriptions to sync their menstrual cycles. Then, the donor will begin to take injections to stimulate ova production. The window of time available for an egg to be harvested, fertilized and successfully implanted, so the synchronization of menstrual cycles means that the recipient is at the most likely time for implantation. The donor will have an outpatient procedure to harvest her eggs, which will then be fertilized with sperm in vitro. Once the embryos are ready, the doctor will transfer them to the recipient’s womb at the time of the cycle when implantation will be most likely. The recipient will then take one days bed rest and two days of rest and a pregnancy test will be performed 10 to 12 days after the transfer of embryos.
Frequently Asked Questions
What actually happens during hyperstimulation of the ovaries?
The patient will take injectable FSH (follicle stimulating hormone) for eight to eleven days, depending on how long the follicles take to mature. This hormone is produced naturally in a woman’s body causing one egg to develop per cycle. Taking the injectable FSH causes several follicles to develop at once, at approximately the same rate. The development is monitored with vaginal ultrasounds and following the patient’s levels of estradiol and progesterone. FSH brand names include Repronex, Follistim, Menopur, Gonal-F and Bravelle. The patient injects herself daily.
What happens during egg retrieval?
When the follicles have developed enough to be harvested, the patient attends an appointment where she is anesthetized and prepared for the procedure. Next, the doctor uses an ultrasound probe to guide a needle through the vaginal wall and into the follicle of the ovary. The thin needle draws the follicle fluid, which is then examined by an embryologist to find the eggs. The whole process takes about 20 minutes.
What happens to the eggs?
In the next step, the harvested eggs are then fertilized. If the sperm from the potential father, or in some cases, anonymous donor, has normal functionality, the eggs and sperm are placed together in a dish with a nutrient fluid, then incubated overnight to fertilize normally. If the sperm functionality is suboptimal, an embryologist uses Intracytoplasmic Sperm Injection to inject a single sperm into a single egg with an extremely precise glass needle. Once fertilization is complete, the embryos are assessed and prepared to be transferred to the patient’s uterus.
How are the embryos transferred back to the uterus?
The doctor and the patient will discuss the number of embryos to be transferred. The number of successfully fertilized eggs usually determines the number of eggs to be placed in the uterus. Embryos are transferred to the uterus with transabdominal ultrasound guidance. This process does not require anesthesia, but it can cause minor cervical or uterine discomfort. Following transfer, the patient is advised to take at least one days bed rest and two or three additional days of rest, then 10 to 12 days later, two pregnancy tests are scheduled to confirm success. Once two positive tests are completed, an obstetrical ultrasound is ordered to show the sac, fetal pole, yolk sac and fetal heart rate.
Built into this technology there is a microscope with a powerful camera that allows the uninterrupted monitoring of the embryo during its first hours of life. In this way, we can keep a close eye on the embryo, from the moment when the oocyte is inseminated and begins to divide into smaller and smaller cells, until it can be transferred to the uterus.
Orthopedics Stem Cell
Research on mesenchymal stem cells regenerative properties in knee osteoarthritis. In these studies, researchers suggest that Stem Cell Therapy has the potential to regenerate lost cartilage, stop and reverse cartilage degeneration, provide pain relief, and improve patient mobility.
Stem Cell Therapy as an Alternative to Rotator Cuff & Shoulder Replacement Surgery. Stem cell therapy may offer an excellent alternative for patients looking to avoid shoulder joint replacement surgery, as well as many other surgical treatments for shoulder pain.
If you suffer from chronic or acute ankle pain or instability due to arthritis, cartilage loss, ligament strain or tear, or tendon damage, then you may benefit from non-surgical stem cell treatments or stem cell-enhanced surgery.
Patients now have a minimally invasive option. Stem cell therapy for back pain and disc herniations can potentially repair the damaged disc or facet joint, restore function, rehydrate the disc, and ultimately alleviate chronic pain.
Anti-Aging Stem Cell
Stem cell therapy and PRP therapy have been shown to be most effective for: Those in the early stages of hair loss, patients who are not viable candidates for surgery and women who prefer to avoid hair surgery.
Aesthetic Anti-Aging. The Aesthetic Stem Cell Localized Treatment is a non-surgical minimally invasive procedure to enhance the appearance of aging skin and hair restoration. This all-natural technique combines dermal injections of bone marrow or adipose tissue derived stem cells and growth factors.
Fertility Stem Cell
The stem cells used for treatment of a thin endometrium include mesenchymal stem cells. In addition, successful repair of the endometrium in pregnancy with stem cells has been reported previously.
Low Ovarian Reserve (PRP)
The treatment uses PRP (Platelet-Rich-Plasma), which with stem cell therapy is the novel therapeutic approach for restoring the quality of the ovarian reserve.Your PRP will contain a physiologic balance of platelets, growth factors and white blood cells tailored specifically for you.
Punta Mita Hospital
Punta Mita Hospital - Genesis Cell